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Sarclisa (isatuximab)

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How is SARCLISA® taken?

How is SARCLISA® taken?1

Your doctor or nurse will give you SARCLISA® in your vein (intravenously) as a drip infusion. Your doctor will determine your dose of SARCLISA® based on your body weight. The recommended dose is 10 mg/kg of your body weight. 

How Often Will I Take SARCLISA®?

SARCLISA® is given in treatment cycles of 28 days (4 weeks) in combination with either pomalidomide and dexamethasone or carfilzomib and dexamethasone.

A graphic depicting SARCLISA® treatment cycles. In Cycle 1, SARCLISA® is administered weekly on days 1, 8, 15, and 22. In Cycle 2 and beyond, SARCLISA® is administered every 2 weeks on days 1 and 15.

While you are taking SARCLISA®, your doctor will monitor you and continue your SARCLISA® treatment for as long as you benefit from it and can tolerate the potential side effects. 

Other Medications

SARCLISA® is given in combination with two other drug combinations: pomalidomide and dexamethasone or carfilzomib and dexamethasone.

You will also receive other medicines before your infusion of SARCLISA® to help reduce the risk of possible infusion-related reactions.

See the Starting Treatment with SARCLISA® tab for more information.

Starting Treatment with SARCLISA®1

Before starting your SARCLISA® treatment, it is important to tell your healthcare professional if you are taking any other medications, including any prescription or over-the-counter drugs, vitamins, minerals, natural supplements or alternative medicines. Tell your doctor or nurse if you have ever taken medicine for your heart, and talk about any health conditions or problems you may have.

How Should I Prepare for My Infusion Appointment?

You must receive the following medicines before infusion of SARCLISA® to help reduce possible infusion-related reactions:

Antihistamine to reduce allergic reactions

Corticosteroid to reduce inflammation

Medicine to reduce pain and fever

What if I miss a dose of SARCLISA®?1

To make sure your treatment works, you must go to all your appointments. If you miss an appointment, call your doctor or nurse as soon as possible to reschedule it. Your doctor or nurse will decide how your treatment should be continued.

Reference

  1. PrSARCLISA® Product Monograph. Sanofi Canada. January 12, 2024.

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